What is gout?
Gout is caused by deposits of uric acid in connective tissue, often in joints of the feet and ankles, and can lead to inflammatory arthritis. Symptoms include swelling, redness, stiffness and severe pain. Although attacks of gout can subside in a few days, repeated attacks can cause permanent joint damage and the disease frequently results in substantial disability.
Foods rich in purines, like red meat, have been associated with an increased risk of gout. Purine can lead to high levels of uric acid, which can build up in the joints and crystallize, causing an attack.
Treatment includes pain-relieving drugs such as non-steroidal anti-inflammatory drugs (NSAIDs) and for more serious outbreaks, corticosteroid medication. Most people with gout eventually require long-term preventative medications.
Why do people experience attacks of gout?
It is not entirely clear, but experts think there are certain triggering factors that make the uric acid more crystallized in tissues. Those triggering factors have been thought to be binge drinking or binge eating of high-purine foods, and perhaps joint trauma. However, these factors have not been well proven in clinical studies.
How is gout diagnosed?
Gout is diagnosed based on the characteristic of the attacks, such as swelling, redness and stiffness in the joints. However, the definitive diagnosis is based on the visualization of uric acid crystals under microscope from joint fluid. That is obtained with by putting a needle into an affected joint by a rheumatologist.